In-life upgrade to Windows 10 is *NOT* recommended at this time. 

Windows 10: 

Junos Pulse v4 : incompatible
GTA Helpdesk : Requires upgrade
SS 7.1 : incompatible
APC(Schnider electric) : Multiple incompatibilities
DSM y6.2 Plug-ins : issues multiple
LXI Hardware : issues multiple

OSX El Capitan:

Certain FTDI and CTDI devices : issues multiple. 
Older firewire interface cards : issues multiple.